Prednisone is prescribed by a doctor and works by reducing swelling and inflammation and changing the way in which the immune system works. generic prednisone online It can also cause more serious side effects like vision problems, depression, and vomiting. If you are taking Prednisone for a long term condition keep in mind that Prednisone is treating the symptoms but will not cure your condition. Taking Prednisone for long periods of time may increase the chances of developing osteoporosis.